- The Green Environment Research Center focuses on research related to sustainable resource management in communities and cities with goal of supporting enhanced living standards.
- The Dr. Hussein El-Sayyed Center for Scientific Research is concerned with scientific and applied research development centered around approved University research themes and research priorities.
- The Centre for Applied Studies for the Affairs of the Two Holy Mosques (Haramain) aims to provide research and development on topics related to the Two Holy Mosques, transform knowledge between the center and UPM, and organize seminars and conferences>
- The Artificial Intelligence and Emerging Technologies Research Center has been established in collaboration with Ministry of Communication and Information Technology to become the Smart Hub in Madinah. It harnesses the power of machine learning to integrated artificial intelligence (AI) into government services and city experiences to improve our overall quality of life.